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The glucagon agonism increases energy expenditure (burning more calories), while GLP-1 and GIP agonism suppress appetite

Statistical analysis of the experimental findings included a trial product estimate that evaluated the treatment effect in the participants based on data that was collected through the 32 week treatment period

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Other therapies were linked to increased adverse events such as stroke [11], hyperkalemia [13,15], hypotension [13], acute kidney injury (AKI) [15], and major adverse cardiovascular events (MACE) [14]